Tag Archives: research

Breaking Down The Brain: The Most Complex Neural Map Ever, Now Complete

Investigators at the forefront of neuroscience have just unveiled the most comprehensive neural map ever created – a milestone achievement comparable in scope and impact to the Human Genome Project.

As part of the MICrONS (Machine Intelligence from Cortical Networks) project – funded by the U.S. Defense Advanced Research Projects Agency (DARPA) under the BRAIN Initiative – scientists have completed the most detailed reconstruction to date of a mammalian brain region. The collaborative effort brought together over 150 researchers across multiple institutions to focus on a one-cubic-millimeter section of mouse visual cortex.

Despite its size being smaller than a grain of rice, the mapped volume contains approximately 200,000 cells, four kilometers of axons, and more than 523 million synapses. It is the most comprehensive cellular and synaptic wiring diagram ever produced for a piece of mammalian brain tissue and the first to integrate both structural and functional data at this scale.

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GPT-4b Enters The Laboratory: OpenAI’s New Model Takes On Longevity Science


Over the past year, OpenAI has dominated headlines with ChatGPT and breakthroughs in generative AI. Now, the company has quietly entered the laboratory, and its first biological research initiative signals a profound shift in longevity science.

In collaboration with Retro Biosciences, OpenAI has developed GPT-4b micro, a specialized AI model that surpasses human capabilities in stem cell research. This venture into biological engineering marks a decisive step beyond language processing, and the results are remarkable. Early testing shows that the model achieves cellular reprogramming with 50 times greater efficiency than conventional methods, rewriting established rules of cellular biology.

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Best of ’23: A4M Reader’s Choice Award

A year of incredible progress, 2023 saw scientific breakthroughs abound. From revelations in epigenetic reprogramming and cellular biology to advancements in medical artificial intelligence technology, the longevity and anti-aging medicine movement forged forward at breakneck speed — and we did our best to keep pace.

So that you, valued members of our community of innovative health professionals, never missed a beat. Armed with the latest research takeaways, best practices, and breaking news, A4M Blog readers always stay ahead of the curve.

Stepping into 2024, we reflect on the monumental discoveries unlocked across the longevity landscape last year and the ones you found most captivating. We’ve gathered 2023’s most popular articles and hope you help us determine the A4M Reader’s Choice Award winner by casting your vote below! And the nominees are…

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