Aging and the Gut: What the Microbiome May Reveal About Biological Age

Aging and the Gut: What the Microbiome May Reveal About Biological Age

Could the secret to aging more slowly be hiding in your gut? Scientists are looking at the gut microbiome to better understand the pace of biological aging – and what they’re finding could have implications for the microbiome’s role in longevity and its potential as a marker of biological age.

In a study published in Scientific Reports, researchers at the University of Hawaiʻi at Mānoa found that a model based on differences in gut bacterial communities accounted for approximately 15% of the variation in participants’ biological aging rates. The results suggest that the gut microbiome, the vast community of microorganisms living in the digestive system, may provide valuable clues about aging at the molecular level.

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T Cells and Longevity: A Closer Look at the Immune Signature of Healthy Aging

T Cells and Longevity: A Closer Look at the Immune Signature of Healthy Aging

What does healthy aging look like? Emerging science suggests that T cells, other immune-cell populations, and blood-protein signatures may offer a snapshot. New research into age-related changes in T cells and the possibility that particular immune-cell populations, along with blood-protein signatures, could help identify patterns associated with longevity, is bringing scientists closer to understanding what distinguishes healthy aging from disease-associated aging on a cellular level. These findings may also help explain why some people remain healthier longer while others are more prone to age-related conditions.

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Why PCOS/PMOS May Require a Lifespan Approach to Metabolic Health

Beyond Menopause: Why PCOS/PMOS May Require a Lifespan Approach to Metabolic Health

In the context of longevity medicine, menopause is not a finish line for metabolic health but rather a shift in how we need to monitor it.

That’s the philosophy of Angela Mazza, DO, ABAARM, FAMMFM, ECNU, a triple board-certified endocrinologist, anti-aging and regenerative medicine specialist, and thyroid expert known for her integrative, functional approach to metabolic and hormonal health. Menopause may mark the end of the reproductive years, Dr. Mazza maintains, but it’s also a time of metabolic changes that call for a new approach to monitoring health.

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