Why PCOS/PMOS May Require a Lifespan Approach to Metabolic Health

Beyond Menopause: Why PCOS/PMOS May Require a Lifespan Approach to Metabolic Health

In the context of longevity medicine, menopause is not a finish line for metabolic health but rather a shift in how we need to monitor it.

That’s the philosophy of Angela Mazza, DO, ABAARM, FAMMFM, ECNU, a triple board-certified endocrinologist, anti-aging and regenerative medicine specialist, and thyroid expert known for her integrative, functional approach to metabolic and hormonal health. Menopause may mark the end of the reproductive years, Dr. Mazza maintains, but it’s also a time of metabolic changes that call for a new approach to monitoring health.

Continue reading →

Reproductive History and Longevity

Reproductive History and Longevity: What Epigenetic Clocks Reveal About Women’s Health

Menopause Awareness Month is observed every October, a global initiative that aims to increase understanding of menopause, highlight symptoms, and promote supportive resources for those experiencing the transition. This October, a newly published study is shedding light on how reproductive history – particularly menopause timing – relates to biological aging measured by DNA methylation clocks. The study adds to research exploring the relationship between reproductive health and biological aging, raising questions about how these findings may eventually inform women’s health assessment.

Continue reading →

The Lipidome of Aging

The Lipidome of Aging: Could Lipid Metabolism Reveal New Clues to Longevity?

Lipids are known to be vital for cellular function; now, researchers are looking at the role they may play in influencing the aging process. Profiling lipids and targeting lipid metabolism, scientists say, could expand our understanding of longevity medicine and how to maintain a better healthspan. Lipidomics – the comprehensive study of lipids – has already revealed molecular distinctions in long-lived individuals and aging models, offering potential biomarkers and targets for healthy aging.

Continue reading →