Category Archives: Immune Health

Best of ’23: A4M Reader’s Choice Award

A year of incredible progress, 2023 saw scientific breakthroughs abound. From revelations in epigenetic reprogramming and cellular biology to advancements in medical artificial intelligence technology, the longevity and anti-aging medicine movement forged forward at breakneck speed — and we did our best to keep pace.

So that you, valued members of our community of innovative health professionals, never missed a beat. Armed with the latest research takeaways, best practices, and breaking news, A4M Blog readers always stay ahead of the curve.

Stepping into 2024, we reflect on the monumental discoveries unlocked across the longevity landscape last year and the ones you found most captivating. We’ve gathered 2023’s most popular articles and hope you help us determine the A4M Reader’s Choice Award winner by casting your vote below! And the nominees are…

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Predicting Disease Susceptibility Through Changes in Cognitive Performance

Cognitive function and other physiological factors, such as stress levels, have long been associated with physiological health and immunocompetence. Markers of cognitive function, such as reaction time, vigilance, and processing speed, are central to human ability and optimal performance. Variability in these measures is common, as numerous environmental, physical, and mental factors can modify them, including sleep quality, dietary patterns, and other lifestyle choices.

A burgeoning body of scientific evidence suggests that intra-individual variability reaction time and other cognitive performance markers may reflect neurobiological disturbances and, thus, have valuable prognostic significance. Prior research has shown that a heightened variability in reaction time is explicitly associated with greater mortality risk in both younger and older adults. Now, the results of a recent 2022 study reveal a potential connection between cognitive performance and disease susceptibility that could transform our understanding of and approach to the brain-immune system pathway.

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