Genetics vs. Lifespan Where Do Genes Fit

Genetics vs. Lifespan: Where Do Genes Fit?

There’s a lot that can be done to increase longevity: maintain a healthy diet, exercise regularly, prioritize sleep, manage stress and mental health, avoid harmful substances, cultivate social connections, practice positivity, and pay attention to cellular health and micronutrition. But once extrinsic factors — such as violence, accidents, infections, and similar events — are taken out of the equation, genetics plays its full role in determining how long (and how healthy) a lifespan may be. Researchers are working to better understand this role, and their findings are already having an impact on what can be done to ensure a longer, healthier, more satisfying life.

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Blood Will Tell Longevity Secrets

Blood Will Tell: Longevity Secrets May Be Hiding in Your Veins

Biological age — the measure of how fast your body and cells are aging — reflects the body’s overall health and functional state at the cellular, tissue, and organ levels. It’s often considered a more reliable indicator of longevity than chronological age, and it is measured using biomarkers. Increasingly, those biomarkers are being found in blood, and researchers are discovering that blood has a lot to reveal about health, longevity, and aging.

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Astronauts, Zombies, and Unwanted Guests

Astronauts, Zombies, and Unwanted Guests: A Look Inside Inflammaging

Inflammaging is an interior perfect storm where immune system remodeling, cellular aging, or senescence, and loss of control over systemic inflammation trigger chronic overstimulation of the innate immune system. As humans age and the immune system declines, immune responses become overactive and less precise, producing pro-inflammatory cytokines that drive inflammaging and maintain a persistent low-grade inflammation that contributes to age-related diseases and functional decline.

For some humans, this is an acceptable situation, and they’ve got the rocking chairs set up on the porch, ready to fade into their declining years riddled with aches, pains, and chronic system failure. For the rest of us, science is constantly opening new doors that lead to a better understanding of inflammaging, and how to counter or even avoid it.

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