Tag Archives: Aging

Reversing the Biological Clock

While the current increasingly aging population and enhanced human lifespan are signs of great advancement in medical technology, population aging also contributes to a variety of socioeconomic, environmental, and healthcare-related difficulties, significantly straining the global economy and healthcare system. The medical community began investigating potential biomedical strategies of reversing the aging process several years ago in the hopes of diminishing cognitive decline, weakening of the immune system, and other negative effects of biological aging. In doing so, researchers have made significant discoveries in the field, one of which now provides a definitive basis of measurement for determining biological age – the epigenetic clock.

Developed by Dr. Steve Horvath, professor of Human Genetics and Biostatistics at UCLA, the epigenetic clock utilizes the body’s epigenome and specifically, changes in DNA methylation state to determine a person’s biological age, which may often exceed or fall behind their chronological age. Dr. Horvath’s discovery has helped to elucidate novel aspects of the aging process and deepen our current understanding, promoting further research efforts aimed at uncovering the complexities of reversing systemic aging. Thus far, attempts at the reversal of biological aging have not been confirmed by epigenetic age changes although the latest trial results from California implicate the potential to effectively reverse the aging process for the first time.

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The Importance of Physical Activity in Middle Age

The benefits of regular physical activity are well-established and well-documented, spurring public health efforts nationwide and urging the population to meet at least minimum exercise guidelines. Prior research has indicated that routine physical activity may decrease the risk for all-cause mortality, cardiovascular disease, and even certain cancers. However, most data stems from observational studies which assess physical activity at a single point in time and its effects on subsequent mortality and chronic disease outcomes.

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Carbohydrate Restriction for Delaying the Aging Process

In a growing aging population, increasing life expectancy is becoming a secondary concern to mitigating age-related disease and the associated repercussions. Improving health outcomes for rising older population is necessary to decrease the socio-economic burden of age-related disease, while promoting overall population health. Although the human lifespan has greatly expanded over the past century, good health and its maintenance remain topics of importance. Recently, dietary solutions to quelling the aging process have surged in popularity, with intermittent fasting, calorie restriction, and other diet plans spearheading the movement.

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