The Role of Sirtuins in Longevity

Despite strenuous controversies, the field of sirtuin research is growing with an increasing number of recent studies revealing their promising connection to longevity. After many years of investigation, understanding of the activity of the silent information regulator 2 (Sir2) family (‘sirtuins’) has greatly expanded, proving its significant involvement in the regulation of many fundamental biological processes. Dr. Leonard Guarente, co-founder of Elysium Health and director of MIT’s Glenn Center for Biology of Aging, stands at the forefront of sirtuin research efforts.

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The Connection Between the Gut and Mental Health

In the past few years, the connection between the brain, gut, and microbiome has become an increasingly examined topic in the medical research community. As more research continues to prove this bidirectional link, there is a growing awareness of the importance of gut health not just for gastrointestinal health but also for overall physical and mental wellbeing. Studies of the connection between the gut and physical health have revealed the powerful effects of the microbiome on the immune system, mood, energy levels, and a range of other bodily aspects.

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Preventing Dementia in Patients with Mild Cognitive Impairment

According to data from the American Academy of Neurology (AAN), an estimated 6% of people worldwide suffer from mild cognitive impairment (MCI) in their 60s, and 37% are affected by age 85. Although patients with mild cognitive impairment have an increased risk of developing dementia, the condition does not always worsen and growing research aims to determine the underlying mechanisms linking the two. The progression from MCI, a slight but noticeable change in cognitive function, to dementia is not automatic; about 15% of MCI cases develop into dementia.

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