Category Archives: Discoveries

Honoring Dr. Stephen Sinatra – A Pioneer in Integrative Cardiology 

June 24, 2022

With deep sadness, we share the news of respected integrative cardiologist and former member of the A4M Board of Scientific Advisors, Dr. Stephen Sinatra’s passing. Dr. Sinatra was one of the most highly regarded and sought-after cardiologists whose whole-person approach to cardiovascular care revitalized patients with even the most advanced forms of disease.

A board-certified cardiologist specializing in integrative medicine, Dr. Sinatra was also certified as a bioenergetic psychotherapist and nutrition and anti-aging specialist – making his education and expertise genuinely unparalleled.

During the course of over 40 years of clinical practice, research, and study, Dr. Sinatra obtained numerous certifications, published a dozen best-selling books, and helped discover and develop healing strategies that guide integrative and anti-aging practices today.

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A Look into Senolytic Therapies for Longevity

July 16, 2021

With a focus on extending and improving the human lifespan, the medical community continues to explore potential avenues in longevity. One such development has directed increased attention to the practice of senolytics – or, the process of flushing senescent cells from the body to discard harmful proteins. Senescent cells are malfunctioning, aged cells which can trigger inflammation and dysfunction, developed in response to disease, injury, or cancerous formations. 

These cells can remain in the body, contributing to the development of many diseases and features of aging, such as heart disease, dementia, osteoporosis, and lung disease. Removing senescent cells from mice was found to alleviate insulin resistance, cell dysfunction, and ameliorate other complications in cases of kidney failure and disease.

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Potential for Oxygen Therapy to Reverse Biological Aging Markers

July 9, 2021

Characterized by the progressive loss of physiological capacity resulting in impaired functioning and susceptibility to diseases, the biological aging process at a cellular level has two key hallmark elements: telomere length (TL) shortening and cellular senescence. A variety of therapeutic methods aimed at reversing or slowing down this process continues to be investigated while a novel treatment shows promise – a specialized form of oxygen therapy that may be able to reverse the aforementioned biological markers of aging.

In a new small study published in the Journal of Aging, researchers present potential breakthrough findings. Per their results, hyperbaric oxygen therapy (HBOT) may be an effective method for delaying or even reversing cellular degeneration as it was shown to lengthen telomeres and decrease levels of senescent cells, potentially helping prevent age-related illnesses such as cancer, diabetes, and dementia.

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