Despite strenuous controversies, the field of sirtuin research is growing with an increasing number of recent studies revealing their promising connection to longevity. After many years of investigation, understanding of the activity of the silent information regulator 2 (Sir2) family (‘sirtuins’) has greatly expanded, proving its significant involvement in the regulation of many fundamental biological processes. Dr. Leonard Guarente, co-founder of Elysium Health and director of MIT’s Glenn Center for Biology of Aging, stands at the forefront of sirtuin research efforts.
Category Archives: Brain
Preventing Dementia in Patients with Mild Cognitive Impairment
According to data from the American Academy of Neurology (AAN), an estimated 6% of people worldwide suffer from mild cognitive impairment (MCI) in their 60s, and 37% are affected by age 85. Although patients with mild cognitive impairment have an increased risk of developing dementia, the condition does not always worsen and growing research aims to determine the underlying mechanisms linking the two. The progression from MCI, a slight but noticeable change in cognitive function, to dementia is not automatic; about 15% of MCI cases develop into dementia.
Brain Awareness Month: Probiotics for Mood and Cognitive Function
June marks the beginning of Brain Awareness Month, a global campaign to raise public awareness of Alzheimer’s Disease and other neurodegenerative conditions. Increased recognition of neurological disorders has led to further clinical research and the discovery of important mechanisms of action, risk factors, and indicators of declining cognitive function. More recently, the medical community has focused its efforts on better understanding the gut-brain axis, or the connection between the human microbiome and mental health. Discoveries continue to implicate the crucial role of the gut in promoting and maintaining cognitive function, mental clarity, and a stable mood.