Tag Archives: nutrition

Biomarkers Could Predict Best Diets

A new study, published in the American Journal of Clinical Nutrition, has indicated two biomarkers that can predict the efficacy of certain diets for weight loss: specifically, for people with prediabetes or diabetes.

Through an analysis of over 1,200 adults, researchers discovered that a person’s fasting blood glucose levels, fasting insulin levels, or both, could pinpoint which diets would most likely lead to weight loss. These biomarkers were particularly effective in determining which diets were best for people with pre-diabetes and diabetes.

Each year, millions of us attempt to lose weight through diets, but not all of us succeed. A new study has uncovered two biomarkers that could predict how effective certain diets will be for weight loss, particularly for people with prediabetes or diabetes.

Statistics from the American Diabetes Association indicate that approximately 29.1 million people in the Untied States have diabetes; estimates show that around 75 million people have pre-diabetes, yet almost 90% remain unaware. Type 2 diabetes is the most common form of the condition: the body is unable to effectively use the hormone insulin, which causes high blood glucose levels. For people with prediabetes, blood glucose levels remain higher than normal—yet not high enough to lead to a diagnosis of diabetes.

The researchers in the study believe that a person’s fasting blood glucose and insulin levels could be utilized to help identify the most effective diet for weight loss, after analyzing the data of three dietary clinical trials: the Diet, Obesity, and Genes trial, the OPUS Supermarket intervention (SHOPUS), and the Nutrient-gene interactions in human obesity (NUGENOB) trial. The subjects were all overweight; the researchers evaluated and assessed their fasting blood glucose levels, and fasting insulin levels, in order to determine whether the levels were associated with weight loss in response to certain diets.

These results symbolize a kind of breakthrough in personalized nutrition: among adults with prediabetes, the team found that a diet rich in whole grains, vegetables, and fruits was the most effective for weight loss. For example, in the SHOPUS trial, adults with prediabetes who followed a diet high in the aforementioned foods lost more weight than those who followed a controlled diet. For people with type 2 diabetes, the researchers found that a diet rich in plant-based, “healthy” fats, and low in carbohydrates, was most effective for weight loss.

The team reported that adding participants’ fasting insulin levels to the analysis further strengthened the identified correlations between diet and weight loss, confirming the hypothesis that fasting blood glucose and fasting insulin levels may be biomarkers for weight loss.

Health Benefits for Coffee Drinkers

Research based on 200 previous global studies indicates that frequent coffee drinkers are less likely to get diabetes, heart disease, dementia, and even some cancers. Those who drink three to four cups a day will, in fact, experience health benefits—and experience lower risks of premature death. 

To better understand the effects of coffee on health, Robin Poole—a public health specialist at Britain’s University of Southampton—led a research team in an ‘umbrella review’ of 201 studies based on observational research, and 17 studies based on clinical trials across the world. ‘Umbrella reviews’ consolidate previous analyses, in order to deliver a clearer summary of diverse research on a particular topic.

The research, published in the The BMJ, revealed that drinking coffee was consistently linked with a lower risk of death from all causes, including heart disease. The largest reduction in relative risk of premature death was seen in people consuming three cups a day, compared with non-coffee drinkers. Drinking coffee was also associated with a lower risk of several cancers, including prostate, endometrial, skin and liver cancer, as well as type-2 diabetes, gallstones and gout. The greatest benefit was seen for liver conditions, such as cirrhosis of the liver.

“What we can say is that people who already enjoy moderate amounts of coffee as part of their diet are most probably getting health benefits,” writes Poole. These findings should be reassuring for coffee drinkers; future studies will likely analyze the types and amounts of coffee that confer the maximum health benefits.

The Necessity of Nutrition

With over two-thirds of Americans considered to be overweight or obese, the global obesity epidemic shows no signs of slowing. As diabetes and cardiovascular disease are on the rise, in addition to spikes in other lifestyle-related disorders, it becomes increasingly critical to maintain education surrounding healthy living habits. Yet while physicians are generally considered to be reliable sources regarding nutrition, more than 50% of graduating medical students continue to rate their knowledge as ‘inadequate,’ and only one in eight patients receives counseling from their doctors on dietary health benefits.

A study found that the majority of cardiologists lack current, up-to-date education surrounding nutrition and diet. A report published by the American Journal of Medicine, authored by a dozen healthcare professionals in the United States and Spain, titled “A Deficiency of Nutrition Education and Practice in Cardiology” details that less than a third of cardiologists describe their nutrition knowledge as “mostly up to date” or better. Indeed, while the leading cause of premature death and disability in the United States is heart disease, most cardiologists report inadequate training in nutrition. “Using nutrition as medicine is probably one of the most cost effective ways to treat disease but is incredibly underutilized by healthcare providers,” explained Andrew Freeman, M.D., a cardiologist at National Jewish Health in Denver, and one of the study’s co-authors. “If we could empower healthcare providers with information on how to implement this in daily practice, we could transform healthcare rapidly, prevent healthcare cost explosions, and reduce morbidity and mortality.”

Ninety percent of cardiologists surveyed reported receiving no or minimal nutrition education during cardiovascular fellowship training; 59 percent reported no nutrition education during international medicine training; 31 percent reported no nutrition education throughout medical school. Almost two-thirds of all surveyed cardiologists reported spending three minutes or less per visit discussing nutrition with their patients.

Moreover, another study designed to quantify the required number of hours of nutrition education at U.S. medical schools, in addition to an investigation regarding the types of courses offered, reaffirmed the supposition that medical students receive an inadequate amount of nutrition education. Only 27% of surveyed schools required a course dedicated to nutrition; on average, U.S. medical schools only offer 19.6 hours of nutrition education—across four years of medical school. Other informal polls and anecdotes uphold the studies’ findings, as students assert that nutrition education throughout medical school is, at best, minimal.

Throughout the past several decades, there has been a push towards improving the medical nutrition education that students receive. With suboptimal knowledge about dietary habits, future physicians are selling both themselves and their patients very short. It is imperative to equip health practitioners with the necessary tools and information that they can utilize in their practices, ultimately addressing the root causes of real, pervasive problems. Medical schools have the burden of responsibility to arm their graduates with the tools to tackle the biggest, most acute global health challenges: including obesity and nutrition problems.