Category Archives: Brain

Lecture Notes From Chicago: Precision Hormone And Brain Care In The Spotlight

May 10, 2025

High-level insights from A4M’s latest educational launches.

Chicago hosted the debut of two new clinical programs last weekend — Cognition 360: Where Innovation Meets Brain Health and the Hormone Dosing Therapy Masterclass — bringing together a dynamic group of practitioners for a weekend of advanced, systems-based education. Kudos to the many attendees who built on momentum from Spring Congress, continuing their training across back-to-back events.

Designed to meet the evolving demands of modern clinical practice, both courses delivered practical, protocol-driven content with direct relevance to patient care balancing innovation with immediate application. While the full scope of insights can’t be captured in one recap, the curated lecture notes below highlight some of the most thought-provoking, protocol-driven, and practice-elevating perspectives shared throughout the weekend.

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Breaking Down The Brain: The Most Complex Neural Map Ever, Now Complete

April 13, 2025

Investigators at the forefront of neuroscience have just unveiled the most comprehensive neural map ever created – a milestone achievement comparable in scope and impact to the Human Genome Project.

As part of the MICrONS (Machine Intelligence from Cortical Networks) project – funded by the U.S. Defense Advanced Research Projects Agency (DARPA) under the BRAIN Initiative – scientists have completed the most detailed reconstruction to date of a mammalian brain region. The collaborative effort brought together over 150 researchers across multiple institutions to focus on a one-cubic-millimeter section of mouse visual cortex.

Despite its size being smaller than a grain of rice, the mapped volume contains approximately 200,000 cells, four kilometers of axons, and more than 523 million synapses. It is the most comprehensive cellular and synaptic wiring diagram ever produced for a piece of mammalian brain tissue and the first to integrate both structural and functional data at this scale.

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Unlocking Brain Health: The Glymphatic System's Role in Reversing Neurodegeneration

Deep Cleaning ‘Dirty Brains’: Reversing Neurodegeneration Via The Glymphatic System

August 24, 2024

Neurodegenerative diseases, with Alzheimer’s disease (AD) at the forefront, pose a formidable challenge to global health. Affecting between 5% and 7% of the population in their lifetime, AD stands as one of the most devastating neurological conditions. In the absence of disease-modifying treatments, researchers have intensified their efforts to explore novel approaches to combat these illnesses.

Recent neuroscientific advancements have shed light on the critical role of the glymphatic system in maintaining brain health and potentially preventing conditions such as Alzheimer’s and Parkinson’s disease (PD).

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