Author Archives: Zuzanna Walter

Metabolic Flexibility: Retraining the Metabolism for Optimal Health

In an attempt to ease digestion, improve energy levels, and promote weight loss, many popular health recommendations focus on increasing metabolic rates. However, while manipulating metabolic speeds may help burn a few extra calories, the efficiency with which the body expends energy largely relies on age and genetic factors. A critical factor is often overlooked in the pursuit of improving metabolism: metabolic flexibility.

A key to optimal wellbeing, longevity, and chronic disease prevention, metabolic flexibility directly measures the body’s ability to respond and adapt to conditional changes in metabolic demands. Access to high-calorie processed foods as part of the standard American diet combined with increasingly sedentary lifestyles have directly impacted the ability of the metabolism to be flexible, and thus, support sustained energy production. Studies have shown that metabolic flexibility can prevent and treat metabolic diseases like diabetes and insulin resistance and help the body run at its optimal levels.

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The Children’s Mental Health Crisis: How Social Isolation in Childhood Alters Brain Development and Function 

Last month, the American Academy of Pediatrics (AAP), the American Academy of Child and Adolescent Psychiatry (AACAP), and Children’s Hospital Association declared a national emergency in children’s mental health. Exacerbated by the COVID-19 pandemic, mounting challenges across the spectrum of childcare have deepened disparities in pediatric primary care and are particularly evident in racial and ethnic minority groups. At the same time, pandemic conditions have led many children to lose their caregivers and forced them into increased social isolation – all of which has culminated in a mental health crisis among the youngest of the population.

Current statistics reveal the urgency of the problem at hand. According to the latest data from the Centers for Disease Control and Prevention, emergency department visits for mental health emergencies rose by 24% in children aged between 5 and 11 years and by 31% in children aged between 12 and 17 years during March through October of 2020. In early 2021, emergency department visits for suspected suicide attempts increased by 51% among girls aged between 12 and 17 years as compared to data from the same period in 2019.

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Improving Stem Cell Treatment with Novel Drug Compound

One of the primary limitations of stem cell treatment and the subject of ongoing research is the challenge of directing stem cells to their necessary destination in the body which has been a subject of ongoing research. Prior studies have discovered that stem cells are drawn to inflammation in the body, however, using this as a therapeutic lure still poses risks. Thus, researchers continue their search for tools that would aid stem cells in their migration and conversion into specific types of cells necessary for optimal treatment. The ability to do so would have a wide range of implications for regenerative medicine as well as the treatment of disorders in which inflammatory signals fade over time, such as chronic spinal cord injury, stroke, or conditions in which the role of inflammation remains unknown.  Continue reading