With many probiotic products on the market and a rising trend in consumption, an increasing number of people are taking probiotic supplements for their purported positive effects. These tangible health benefits have been contested by the medical community, as there is not enough human-based clinical data to support their efficacy in the treatment of a variety of conditions. Making strong recommendations to patients is difficult at this stage due to the lack of research, however, probiotics are viewed as generally well-tolerated and considered safe. Upcoming guidelines from the American Gastroenterological Association (AGA) hope to elucidate the issues related to probiotic supplementation and will be the first clinical recommendations to clarify specific indications for probiotics.
Disease, premature death, and early signs of aging have all been linked to the growing number of environmental pollutants affecting the global population. Recent research has found that previous estimates of deaths caused by environmental pollution have been greatly underestimated. The study revealed a total of 8.8 million deaths attributable to air pollution each year worldwide. The detrimental effects of this ubiquitous issue on both environmental and human health are well-known, however, new research aims to determine whether exposure to pollutants can accelerate aging at the cellular level.
Despite strenuous controversies, the field of sirtuin research is growing with an increasing number of recent studies revealing their promising connection to longevity. After many years of investigation, understanding of the activity of the silent information regulator 2 (Sir2) family (‘sirtuins’) has greatly expanded, proving its significant involvement in the regulation of many fundamental biological processes. Dr. Leonard Guarente, co-founder of Elysium Health and director of MIT’s Glenn Center for Biology of Aging, stands at the forefront of sirtuin research efforts.