Tag Archives: lifespan

Rapamycin for Longevity: The Anti-Aging Miracle Drug?

Although the human lifespan has increased over recent decades, the human health-span has been unable to keep pace. While we are living longer due to scientific advancements, the number of years we spend without age-related diseases has not increased proportionately.

Lifestyle interventions often recommended too late in life tend not to be sufficient to prevent, halt, or reverse age-related decline. Research scientists are increasingly focusing on potential pharmaceutical interventions to combat the negative aspects of aging. One pathway of exploration aims to repurpose existing medications for geroprotection and is proving remarkably successful in early trials.

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Longevity and Alcohol: Exploring The Complex Connection

Even though drinking alcohol is common among the population, current research has not provided a definitive answer as to the health benefits and consequences of drinking alcohol. On the one hand, drinking alcohol has been repeatedly discussed in scientific papers as protective against certain diseases, such as cardiovascular disease, and light-to-moderate alcohol intake has even been related to reduced mortality risks. On the other hand, several studies suggest that even moderate amounts of alcohol can have a detrimental impact on health, and in most cases, the substance causes more harm than good.

The complexity of the risk relationship between alcohol, health, and longevity continues to confuse patients and clinicians and remains a subject of intense research and controversy. There are very few studies available on the connection between alcohol and longevity, but emerging scientific findings aim to add to the body of knowledge and outline the adverse effects of alcohol on biological aging.

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Autophagy for Longer Lifespan?

Over time, damaged and dysfunctional components of the body’s cells accumulate leading to a potential buildup of cellular debris which can permanently alter the genes, structure, and function of cells. Clearing away these parts is essential for maintaining optimal cellular function and happens naturally in the body during a complex process called autophagy. Scientists are currently investigating the potential benefits and risks involved with inducing autophagy, which has been linked to several positive health effects including the improvement of cellular health and promotion of an elongated human lifespan. Research in this field remains in its early stages yet some studies have revealed promising results that could shape future approaches to functional medicine.

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