Tag Archives: chronic inflammation

The Future of CIRS

April 7, 2023

By: Andrew Heyman, MD, MHSA

It is difficult, if not dangerous, to predict the future. But trends and good data can point the way toward possibilities and probabilities. There is momentum building in our understanding of Chronic Inflammatory Response  Syndrome (CIRS), and the science has grown exponentially in the past 18 months thanks to transcriptomics. This new knowledge is sweeping our efforts forward in a  more defined direction while we hone our understanding of the disease. The future is coming into focus.

There are also larger moving parts within the general CIRS practitioner community and even external social and market forces that seem to be creating a set of likely outcomes that are both exciting and important.

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The Brain On Fire: Is Depression An Inflammation-Based Disease?

March 17, 2023

Complex, heterogenous, and often debilitating, depression is a multifaceted condition that affects millions of people worldwide. According to current statistics, one in five Americans will experience major depressive disorder (MDD) in their lifetime, and many will not find relief from current therapeutic approaches. While there is an ever-growing list of potential causes of MDD, recent research suggests that inflammation in the body may be a contributing factor to the development and severity of depression. And the latest clinical trial data suggest that targeting and treating inflammation as the root cause may help clinicians provide more precise, personalized care to patients struggling with depression and help them achieve lasting mental and physical wellness.

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Where Our Worlds Collide: The Systemic Storm of Inflammation, Cardiovascular Disease and Psoriasis 

July 8, 2022

A Partner Blog from Three of the Tarsus Family of Brands: American Academy of Anti-Aging Medicine, Cardiometabolic Health Congress, and LiVDerm.

A review published in May 2021 in the European Cardiology Review sought to elucidate the various potential factors, mechanisms, or processes linking cardiovascular disease (CVD) and psoriasis. Observational relationships between these two diseases include: an increased independent association between cardiovascular disease and severe psoriasis in younger patients; a higher mortality rate in patients with psoriasis with an overall five-year reduction in life expectancy; a parallel rise in psoriasis severity and CVD risk factors such as hypertension, diabetes, hyperlipidemia, and nonalcoholic fatty liver disease; a higher rate of both CVD and psoriasis in geographical populations furthest from the equator; and the majority of deaths in patients with psoriasis being attributed to cardiovascular or cerebrovascular events. The authors of the review noted that severe psoriasis was more strongly linked to cardiovascular-related mortality than was mild or moderate psoriasis.

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