Category Archives: Nutrition

Turmeric: Boosting Memory & Mood

Curcumin, the most active substance of turmeric, is commonly used in Indian cooking as a primary spice—and often used in mustard, butter, and cheese. Findings of a new study have revealed that it may also help improve memory and mood.

In a study published in the American Journal of Geriatric Psychiatry last week, Gary Small, from UCLA’s Longevity Center, and fellow researchers found that giving 90 milligrams of curcumin daily improved the memory and mood of older adults with mild memory complaints.

The subjects were given standardised cognitive assessments at the start of the study, and at six month intervals. The curcumin levels in the blood were monitored at the start of the study and after 18 months. Thirty of the volunteers underwent positron emission tomography, or PET scans, to determine the levels of amyloid and tau in their brains at the start of the study and after 18 months.

The findings revealed that people who took curcumin experienced significant improvements in their memory and attention abilities, while the subjects who received placebo did not, Small said. People taking curcumin improved by 28 per cent over the 18 months in their memory tests. There were mild improvements in mood for people taking curcumin. The PET scans of their brain showed significantly less amyloid and tau signals in the amygdala and hypothalamus than those who took placebos. The amygdala and hypothalamus are regions of the brain that control several memory and emotional functions.

The researchers also found less signals of tau and amyloid proteins in those who were given curcumin supplements: proteins linked to the development of Alzheimer’s Disease. “Exactly how curcumin may exert cognitive and mood effects is not certain, but several potential mechanisms could explain our findings,” researchers wrote in their study. “Curcumin reduces inflammation, and heightened brain inflammation has been linked to both Alzheimer disease and major depression.”

Countries such as India, where people eat curcumin at levels of about 100 mg to 200 mg a day over long periods of time, have low prevalence of cancer. Researchers suspect this may have something to do with the health benefits of turmeric.

Earlier studies have shown other possible beneficial effects of consuming curcumin on health. In a 2001 study involving patients with precancerous changes, investigators found that curcumin could stop precancerous changes in organs from developing into cancer. “Our results also suggest a biologic effect of curcumin in the chemoprevention of cancer,” the researchers wrote in their study.

Lab tests also showed that turmeric extract that contains curcumin may help stabilize colorectal cancer that did not benefit from other forms of treatment. Other preliminary lab studies also suggest that turmeric may provide protection against high cholesterol, colitis, stomach ulcers, diabetes, depression, and viral infections.

The Benefits of Mindful Eating

Recent studies indicate that meal timing and frequency may impact cardiovascular health, and disease risks. While eating patterns vary from person to person, research indicates that effective management of cardiometabolic health should focus on ‘intentional eating’–paying attention to standardize eating times, meal sizes, and food content. 

One of the primary critical factors in evaluating the effect of meal frequency and timing on cardiovascular health was what constituted a meal that potentially impacted metabolism. Data shows that distributing calories over a defined period of the day, coupled with maintaining a consistent overnight fast period, could ultimately yield positive benefits surrounding cardiometabolic health–in addition to eating a larger portion of one’s daily caloric intake earlier in the day.

Skipping meals and snacking, which have become increasingly prevalent, have various effects on cardiometabolic health markers: namely obesity, lipid profile, insulin resistance, and blood pressure. Because irregular eating patterns do not lead to a healthy cardiometabolic profile, intentional eating–with mindful attention to the timing and frequency of eating occasions–will lead to a healthier lifestyle. Most importantly, planning each meal with a variety of healthy foods, and timing meals, can help manage hunger, achieve desired portion control, and improve nutrition quality.

Biomarkers Could Predict Best Diets

A new study, published in the American Journal of Clinical Nutrition, has indicated two biomarkers that can predict the efficacy of certain diets for weight loss: specifically, for people with prediabetes or diabetes.

Through an analysis of over 1,200 adults, researchers discovered that a person’s fasting blood glucose levels, fasting insulin levels, or both, could pinpoint which diets would most likely lead to weight loss. These biomarkers were particularly effective in determining which diets were best for people with pre-diabetes and diabetes.

Each year, millions of us attempt to lose weight through diets, but not all of us succeed. A new study has uncovered two biomarkers that could predict how effective certain diets will be for weight loss, particularly for people with prediabetes or diabetes.

Statistics from the American Diabetes Association indicate that approximately 29.1 million people in the Untied States have diabetes; estimates show that around 75 million people have pre-diabetes, yet almost 90% remain unaware. Type 2 diabetes is the most common form of the condition: the body is unable to effectively use the hormone insulin, which causes high blood glucose levels. For people with prediabetes, blood glucose levels remain higher than normal—yet not high enough to lead to a diagnosis of diabetes.

The researchers in the study believe that a person’s fasting blood glucose and insulin levels could be utilized to help identify the most effective diet for weight loss, after analyzing the data of three dietary clinical trials: the Diet, Obesity, and Genes trial, the OPUS Supermarket intervention (SHOPUS), and the Nutrient-gene interactions in human obesity (NUGENOB) trial. The subjects were all overweight; the researchers evaluated and assessed their fasting blood glucose levels, and fasting insulin levels, in order to determine whether the levels were associated with weight loss in response to certain diets.

These results symbolize a kind of breakthrough in personalized nutrition: among adults with prediabetes, the team found that a diet rich in whole grains, vegetables, and fruits was the most effective for weight loss. For example, in the SHOPUS trial, adults with prediabetes who followed a diet high in the aforementioned foods lost more weight than those who followed a controlled diet. For people with type 2 diabetes, the researchers found that a diet rich in plant-based, “healthy” fats, and low in carbohydrates, was most effective for weight loss.

The team reported that adding participants’ fasting insulin levels to the analysis further strengthened the identified correlations between diet and weight loss, confirming the hypothesis that fasting blood glucose and fasting insulin levels may be biomarkers for weight loss.