Author Archives: Zuzanna Walter

Gut Bacteria Play a Role in Cancer Tumor Development

In recent years, the role of the gut microbiome in human health and its influence on human diseases – including different types of cancer – has garnered increasing attention. At the same time, its role in cancer treatment has become more apparent with burgeoning evidence of the positive effects associated with gut microbiome modulation, implicating that it may impact patient responses to various cancer therapies.

A growing emphasis on precision medicine makes furthered knowledge and understanding of the microbiome’s influence on immune responses and cancer imperative. The discovery of strategies for manipulating the microbiome, to thereby augment therapeutic responses, relies on understanding the specific factors that influence gut microbiome mechanisms. Although several species of intestinal bacteria have already been linked to the enhanced efficacy of immunotherapies, exactly how the microbiome is able to enhance anti-tumor immunity remains in question.

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Impact of COVID-19 Isolation and Social Distancing on Mental Health

As a method of novel coronavirus disease transmission suppression and an attempt to reduce the risk of infection, social restrictions – such as social distancing and sheltering in place – have been put into place and remain active in the majority of the United States. Such measures have isolated many older adults at home, leaving them with limited contact and social interaction for the duration of the outbreak. As evidenced by global statistics revealing higher death rates among this demographic, the COVID-19 pandemic has been disproportionately affecting older adults.

Current literature suggests that social interaction is an integral component of mental health and wellbeing, while loneliness has been associated with morbidity and mortality in prior research. While the isolating effects of social distancing measures have been felt acutely by the entire population and may be especially profound in older demographics, relatively little scientific evidence on the subject is currently available. A recent study published in the Pan American Journal of Public Health aimed to provide further information on the implications of social distancing measures on patient mental health.

Coping with Coronavirus Isolation

A team of researchers aimed to examine the impact of isolation and social distancing among adults aged 60 and above during the COVID-19 outbreak in the United States. To conduct this analysis, the study’s authors asked convenience sampling respondents to complete a web-administered survey exploring the effects of social distancing on mental health factors, including loneliness, stress, and behavioral changes. In total, data from 833 responses from participants aged 60 and above were included in the sample.

Effects of Social Distancing on Older Patients

Of the total survey respondents, 36% reported being stressed while nearly 43% reported feelings of loneliness. Approximately one-third of participants reported feelings of increased loneliness during the social distancing period specifically. Respondents also reported engaging in more solitary activities and fewer in-person activities, using email and text messages more than usual, and spending more time using technology than before.

The study’s authors noted significant differences between younger patients aged 60-70 and those above the age of 71; changes in physical activity, drinking, recreational drug use, and sleeping pattern were found to differ by age. Participants over the age of 71 showed more resiliency with 74% experiencing little to no stress, according to the authors.

“That’s where older adults have a strength,” lead researcher and clinical associate professor at the University of Georgia’s Institute of Gerontology Kerstin Emerson told HealthDay. “They have life experience and coping mechanisms that we don’t often give them credit for, but that’s part of their wisdom. We can really turn to older adults as examples of how to manage and live through bad periods of history.”

Furthermore, two-thirds of survey respondents reported using more social media than they would before the pandemic began revealing that older adults are actively engaging in other forms of social connection and becoming increasingly comfortable online. However, for some older individuals remote connections may be more difficult to achieve due to a lack of internet or smart device access; Emerson noted that her team’s results don’t reflect the most vulnerable populations socially isolated in rural areas or those without sufficient economic resources.

As social distancing regulations and isolation measures persist across the globe, it is important to consider the effects of these strategies on mental health – especially among older adults in the United States. The latest findings indicate the potential adverse psychiatric effects associated with continued shelter-in-place practices and highlight the need for increased mental health screening among vulnerable populations at this time.

Meet Our August Partner of the Month: Vumedi

VuMedi is the largest video education platform for doctors. A comprehensive resource with over 30,000 videos from medical institutions including Cleveland Clinic, UCSF, Stanford, Columbia and other globally recognized institutions. 450,000 doctors use the platform to educate themselves and ensure they are up to date on practice changing medical advances. VuMedi’s mission is to help clinicians make optimal patient care decisions through comprehensive video education from a variety of trustworthy institutions and practitioners.

VuMedi builds a robust video-sharing community by partnering with doctors, hospitals, meetings and societies to allow for the rapid dissemination of groundbreaking medical information.  VuMedi engages doctors who are publishing cutting edge research, allowing them to distribute their findings quickly to other clinicians around the world, who then take the learnings and apply them as needed across their practices.

VuMedi takes great pride in the trust placed by the medical community in the content we provide. The content is paired with the ability for our technology to target the right communities through a unique, proprietary algorithm paired with a human “education” team of subject matter experts.   Physicians who need to access new topics and research can easily find multiple points of view on the exact subject they are looking to better understand.

VuMedi was founded at the University of California, Berkeley by Roman Giverts. In the ensuing decade, it has focused on ensuring authentic content is delivered in the right way and at the right time to help the medical community deliver the best patient care.  It’s why today, doctors trust VuMedi to provide clinically relevant, succinct presentations of data in a compressed and categorized footprint.

Interested in joining VuMedi’s physician community?  Visit us at www.vumedi.com

Interested in contributing content or partnering at the hospital, meeting society level?  Send us a note [email protected]

*Disclaimer: there is no cost for either of the above!!