Wearables: Potential to Predict Disease

A host of studies and research confirms the burgeoning theory that wearable health technology, an innovation that has progressively gained traction in medical and consumer arenas, can positively affect healthcare and patients’ wellness. Moreover, researchers have found that data from smartwatches have the capabilities to both detect—and even predict—the onset of disease. 

Because a large segment of the population utilizes smartwatches, an enormous amount of data and metrics portray a more comprehensive overview of health, as opposed to a solitary visit to the doctor. Researchers from Stanford University conducted a study during which they gave participants smartwatches, and subsequently analyzed almost a year of the data. Measurements included skin temperature, heart rate, and data collected from sleep.

When analyzing the data, the team found that ‘out-of-the-ordinary measurements’—specifically heart rate—had strong correlations with health issues like the common cold. Additionally, more detailed data was collected from several participants, for two years. Researchers evaluated this data, and chose the four dates during which measurements were out of the ordinary: the heart rate and skin temperature were specifically elevated. During a period when the measurements were abnormal, the participant had developed Lyme disease; during the other periods, he had a fever, or the common old.

These measurements have strong correlations with inflammation, suggesting that the data was able to pinpoint and pick up on signs of inflammation. Other participants who were ill during the period they used smartwatches demonstrated measurements of elevated heart rate and skin temperatures. Moreover, in a separate experiment, the team found that insulin resistance had a connection to body mass index and heart rate—the latter of which was measured by a smartwatch.

The simplicity behind wearing a fitness wristband, and any wearable health technology, can more easily help surgeons detect which patients are at risk for complications. Evidence-based studies have demonstrated that the integration of wireless technology strongly correlates with ‘postoperative quality-of-life data,’ and reinforces research that surgeons should consistently track their patients’ results and quality of life.

These findings reaffirm the belief that surgeons have the capability to routinely measure patient-centered results–including anxiety, postoperative pain, and the ease with which patients can perform daily tasks and activities. While surgeons do not regularly practice this type of aftercare, and follow up on patients’ recovery, this monitoring system establishes an exciting and inventive kind of versatility, portability, and ultimate healthcare awareness that should be incorporated and put into practice.

The idea that smartwatches can predict and detect disease could become a widespread phenomenon, which would ultimately become an accessible and convenient tool for diagnosis. Wearables may have the potential to eliminate doctor visits, particularly for people who have geographical or monetary difficulties.

The Link Between Parkinson’s & Gut Bacteria

Recent findings have confirmed a long assumed, yet never officially proven, hypothesis regarding a functional link between the gut’s bacteria and the onset of Parkinson’s disease. While previous research has demonstrated strong correlations between the gut and the disease, no research has shown the exact relationship.

One of the world’s most prevalent neurodegenerative disorders, Parkinson’s affects approximately 1 million people in the United States. A progressive and chronic movement disorder, Parkinson’s involves the malfunction and ultimate death of the brain’s vital nerve cells: neurons. As the neurons that typically produce normal levels of dopamine—the chemical that communicates with the segment of the brain that controls coordination and movement—regularly decrease and dopamine levels lessen, a person becomes unable to control movement. Worsening symptoms include the gradual deterioration of motor symptoms: body tremors, bradykinesia/slowness of movement, rigidity, and severe postural instability.

The studies suggest a new, unprecedented way of treating the disease and its symptoms: targeting the gut, rather than the brain, and developing next-generation probiotics: a more sophisticated version than those readily available for purchase and consumption today.

Through conducting trials during which mice were fed certain short-chain fatty acids that are commonly produced by bacteria in the gut, in addition to actual samples of gut bacteria from human Parkinson’s patients and healthy human controls, the team found that the mice either exhibited symptoms, or did not produce symptoms, respectively. The team’s researchers expressed their hope in the possibility of the prescription of drugs that contain bacteria to prevent Parkinson’s, or treat the disease symptoms. Moreover, the studies imply that Parkinson’s is less related to hereditary genetics than environmental factors—including the onset of age.

At A4M, our overarching goal is to treat—and ultimately prevent—the onset of diseases associated with aging. Attend our upcoming events and learn about the advancement of technology and biomedical engineering, coupled with the most recent research & inquiries into methods that optimize the human aging process.
 
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National Alzheimer’s Disease Awareness Month

At A4M/MMI, our mission is to spread awareness surrounding the need for research, funding, and further education in order to prevent age-related diseases. This will not be the last you hear from us concerning Alzheimer’s disease, as it is a topic that both deserves and requires a significant amount of attention.

The month of November has been officially designated as Alzheimer’s Disease Awareness Month, a disease that currently affects more than five million Americans: a number that could potentially skyrocket to 16 million in the next three decades. Not only is Alzheimer’s the sixth-leading cause of death in the country, but the disease also leads to tremendous financial and emotional instabilities, in addition to extensive family strain and stress.

The cognitive losses that accompany Alzheimer’s disease are, at first blush, signs of normal aging: forgetfulness, disorientation, and impairments in functioning that lead to one’s inability to perform basic, rudimentary tasks. Yet these symptoms are merely the tip of the iceberg: depression, anxiety, aggression, and a detachment from reality are some of the emotional and behavioral difficulties caused by Alzheimer’s.

While pharmaceutical medications can alleviate some of the more crippling symptoms of Alzheimer’s, controllable risk factors for Alzheimer’s disease remain unknown; thus, it is not yet possible to reduce chances of developing the disease. While the past two decades have seen significant advances in our understanding of the disease, there is still no cure, nor any way to slow the disease’s progression, or reverse the deterioration.

Current mainstream medical therapy aims to preserve diminishing brain function, yet several drugs are currently being studied through clinical trials, with the hopes of improving memory or slowing the disease’s progression. Continued and increased funding in research is critical, as most scientists and clinicians believe that early detection is the primary way in which to stop the disease’s progression—or even ultimately cure it.

To become further involved with research, funding, or learn more about ways to prevent aging-related diseases, take a look at what being an A4M member means.  Enhancing health is always our top priority, and we believe if you are reading this, it is yours too.