Protein and Lifespan: The Case for an Ad Libitum Diet

The concept of eating for longevity has been around for thousands of years — it was, after all, Hippocrates who advised “Let food be thy medicine” back in the fourth century BCE. Modern health and aging experts agree with the Father of Medicine, but have differing ideas about the kind of diet that provides optimum lifespan benefits. Now that a new study published in Aging Cell shows lifespan benefits associated with an ad libitum diet, some experts may be rethinking their dietary recommendations.

The study found that high-protein, low-carbohydrate diets were associated with an increased risk of disease and mortality in rodent models, suggesting that a more comprehensive evaluation of such regimens should be undertaken. In terms of eating to influence health and lifespan, the study concluded that a low-protein, high-carbohydrate (LPHC) diet, diluted 25% with non-digestible fiber, could be an effective way to improve both health parameters and lifespan.

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“Lean” Into a Longer, Healthier Life: Making the Muscle-Longevity Connection

Can getting stronger help you live longer? Peter Attia, MD, says yes. Dr. Attia, a Stanford-trained physician and co-founder of the premium preventive health and longevity concept Biograph, is one of the most visible figures in longevity medicine. He recently spoke about his firm belief that cardiorespiratory fitness, muscle mass, and strength have a much higher association with longevity than traditional diagnostic health markers.

“The data are pretty clear,” Dr. Attia told 60 Minutes contributing correspondent Norah O’Donnell during a recent interview. “When you look at things like cardiorespiratory fitness, when you look at muscle mass, when you look at strength, they have a much higher association than things like even cholesterol and blood pressure.”

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Featured Sessions and Perspectives from The A4M Women’s Health Summit

The energy from the sold-out 2025 Women’s Health Summit in Scottsdale continues to reverberate. Between October 9-11, practitioners gathered at The Westin Kierland for an intensive deep-dive into menopause medicine, emerging from three days armed with protocols, data, and strategies that directly address the most pressing challenge in women’s healthspan optimization: menopause. 

Our second-ever Summit delivered on its promise to equip providers to empower their patients’ journeys through this consequential and long-lasting hormonal transition. A lineup of leading female health experts presented evidence-based frameworks spanning metabolic health, hormone optimization, genetic influences, musculoskeletal preservation, mental health support, and systemic healthcare reform. Each session provided immediately applicable clinical tools designed to elevate women’s health outcomes in practice.

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