First identified in the early 1990s, the endocannabinoid system (ECS) has emerged as an important neuromodulatory system over recent years. The complex cell-signaling system regulates and controls many bodily functions, active in the body without the use of cannabis. A growing understanding of the ECS and the role it plays in a wide-range of biological pathways has placed it at the center of increasing international research and drug development efforts. As a result, the burgeoning field of ECS-targeted therapeutics and their approved applications in clinical practice are likely to expand exponentially in the near future.

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