Category Archives: Brain

Artificial Sweeteners: Tied to Stroke & Dementia

A new study published in the American Heart Association’s journal Stroke suggests that artificial sweeteners, found in diet sodas, have considerable health risks for both the body and the brain.

The data was collected from the Framingham Heart Study, a project of the National Heart, Lung, and Blood Institute and Boston University, and involved data on 2,888 adults older than 45 and 1,484 adults older than 60 from Framingham, Massachusetts. In the group aged 45-and-older, researchers measured for increased risk of stroke; in the group aged 60-and-older, researchers measured for dementia.

The statistics analyzed how many sugary beverages and artificially sweetened soft drinks each person in the two different age groups drank, between the years 1991 and 2001. That data was than compared against the number of people who suffered from stroke or dementia in the next decade.

Researchers found that—juxtaposed against people who never drank artificially sweetened soft drinks—those who drank one per day were almost three times as likely to have an ischemic stroke. Those who drank one per day were also almost three times as likely to be diagnosed with dementia.

Previous studies have shown a strong association between the intake of sugar-sweetened beverages and a host of adverse health effects, including type 2 diabetes, obesity, and cardiovascular disease. Professor and chair of neurology at the University of Miami Miller School of Medicine Dr. Ralph Sacco confirms that this article “provides further evidence on artificially sweetened beverages and their possibly effects on vascular health…we believe the pathways of which artificially sweetened beverages would affect the brain are probably through vascular mechanisms.”

Moreover, artificial sweeteners have been shown to cause glucose intolerance in mice by altering gut microbiota, and have been associated with dysbiosis and glucose intolerance in humans. The cumulative research strongly indicates that there is no benefit to using artificial sweeteners, or drinking diet soda, compared to regular sucrose or sugary drinks.

To learn more about the gut-immune-brain connection, and the different ways in which various types of inflammation can affect the body and brain, register for Module VII: Autoimmune Disease & Inflammation, from August 10-12.

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